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S3-5
Precision Medicine and Learning Health System
Shih-Feng Tsai, M.D., Ph.D.
Institute of Molecular and Genomic Medicine,
National Health Research Institutes
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Lately there have been increasing interest and discussion about “precision medicine”, in particular its impact on the health care system and biotechnology development. As NGS emerges as a transforming technology in the biomedical fields, massive amounts of genetic data are being amassed by research labs thereby facilitating the progress of rationalized medicine through evidence-based studies on human health and disease. To cope with the increasing complexity and cost of medical care, learning health system (LHS) was proposed as a way of analyzing the issues and providing solutions to continuously improve the system.
In order to meet the demands of developing precision medicine and learning health system, NHRI has spearheaded new initiatives to promote the collaboration between genomics experts, clinician scientists, and policy makers. We are interested in learning how new genomic technology and information systems can be applied to the complex issue of realizing research outcomes for the benefit of patients. First, we have collected biological data in order to understand the heterogeneous nature of a common malignant disease such as liver cancer. Second, we learned from our collaborators about outstanding issues in clinical practice. From there, we designed a research scheme for studying treatment outcome, quality of care, and health economy.
In this presentation, I wish to present the ideas of our integrated approach and share with you some of our data and experiences so far. |
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