專題討論2:腸道微菌叢的熱點議題

S2-1
Fecal microbiota transplantation in Taiwan
Chun-Ying Wu, MD, PhD, MPH, LL.M.
President, Taiwan Microbiota Consortium
Chief, Division of Translational Research
Professor, Division of Gastroenterology & Hepatolog

  Microbiota is associated with many human diseases, such as obesity, metabolic syndrome, cardiovascular diseases, cancer, autoimmune diseases, psychiatric diseases, etc. Fecal microbiota transplantation (FMT) is a measure to transfer gut microbiota from healthy donors to recipients to treat human diseases. The efficacy of FMT has been confirmed in treating recurrent and refractory Clostridium difficile infection, and also suggested in several diseases, such as inflammatory bowel diseases, hepatic encephalopathy, etc.
  To promote FMT in clinical practice and also in medical research, Taiwan Microbiota Consortium (TMC) has devoted many efforts in establishing Taiwan FMT Consensus in March 2018 after one year’s full discussion. Taiwan FMT Consensus has several distinct characteristics as follows. First, it is the first FMT consensus in Asia. Second, the Consensus is made by multiple stakeholders, including medical experts, government officers, clinical physicians, and also public media. Third, the Consensus assures FMT quality via government monitoring. Taiwan FMT Consensus includes several important parts: FMT indications, FMT donor selection, FMT center implementation, FMT material preparation and delivery, post-FMT monitoring and registration.
  About half a year after TMC announcing Taiwan FMT Consensus, Taiwan’s Ministry of Health and Welfare announced FMT as a new technology regulated by Special Regulation in September 2018. The FMT Special Regulation is exactly the same as TMC’s Taiwan FMT Consensus. According to FMT Special Regulation, TMC provided certificated training courses for more than 300 health care providers who plan to conduct FMT in Taiwan. It is a great success for TMC to create such a friendly environment for doing FMT and wish it opens a new ear for more important microbiota clinical studies.
  In this talk, Taiwan FMT Consensus and Special Regulation will be introduced and discussed. For those having interesting to do FMT or to know the new development of FMT, this lecture should be a not-missing one.